Hypoxia & EPO

This section covers research linking hypoxic exposure, breath-hold physiology and EPO response. These studies support the physiological logic that controlled oxygen desaturation can activate pathways relevant to red blood cell adaptation.

de Bruijn, Richardson & Schagatay — Increased erythropoietin concentration after repeated apneas in humans
Link: https://pubmed.ncbi.nlm.nih.gov/18097682/
Kort note: Repeated apneas increased circulating EPO concentration, supporting the breath-hold → hypoxic stimulus → EPO logic.

Europe PMC version — Increased erythropoietin concentration after repeated apneas in humans
Link: https://europepmc.org/article/med/18097682

Oxygen Advantage PDF — de Bruijn repeated apneas / EPO paper
Link: https://oxygenadvantage.co.za/wp-content/uploads/2016/06/De-Bruijn-R-Increased-erythropoietin-concentration-after-repeated-apneas-Eur-Jour-Appl-Phy.pdf